The applications of chromatin immunoprecipitation in the study on the downstream target genes of androgen receptor in prostate cancer cells / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
; (12): 673-677, 2014.
Article
de Zh
| WPRIM
| ID: wpr-454672
Bibliothèque responsable:
WPRO
ABSTRACT
Prostate cancer is one of the most common malignant tumor of male population in the West.Via binding to androgen response element in the genome and interacting with co-regulators,androgen receptor can participate in the development of prostate cancer and the convertion from androgen dependent prostate cancer to androgen independent prostate cancer.Chromatin immunoprecipitation ,coupled with PCR , chip,and high-throughput sequencing ,makes a huge progress in the study on the downstream target genes of androgen receptor and provide a new way to understand the molecular mechanisms of castration -resistant prostate cancer.
Texte intégral:
1
Base de données:
WPRIM
Langue:
Zh
Journal:
Chinese Journal of Laboratory Medicine
Année:
2014
Type de document:
Article