Determination of Psoralen and Isops oralen Contents in Fukangbao Capsul e by HPLC / 中药新药与临床药理
Article
de Zh
| WPRIM
| ID: wpr-570890
Bibliothèque responsable:
WPRO
ABSTRACT
Objective To establish a reversed -phase HPLC m ethod for the determination of psora len and isopsoralen in Fukangbao capsule.Methods The contents of Psoralen and Isopsoralen were assayed on a ODS -C 18 column with a mobile phase of methanol -water(40∶60)at a column temperature of 35℃.The fl ow rate was 1.0mL /min.The detection wave-length was at 247nm.Results The linear ranges of Psoralen and Iso psoralen were 1.05~10.52?g /mL(r =0.9999)and1.02~10.20?g /mL(r =0.9999)respectively.Their recoveries were within 97.5%(Psoralen)and 100.8%(Isopsoralen),and both of their RSD were 0.6%.Conclusion This method is simple,rapid and accu rate and suitable for quantity -limiting control of Fukan gbao capsule.
Texte intégral:
1
Base de données:
WPRIM
Langue:
Zh
Journal:
Traditional Chinese Drug Research & Clinical Pharmacology
Année:
1993
Type de document:
Article