Progresses of magnetic resonance spectroscopy in thalamo-cortical network of juvenile myoclonic epilepsy / 中国医学影像技术
Chinese Journal of Medical Imaging Technology
; (12): 954-958, 2017.
Article
de Zh
| WPRIM
| ID: wpr-619612
Bibliothèque responsable:
WPRO
ABSTRACT
Juvenile myoclonic epilepsy (JME) diagnosed with seizure history,semiology and electroencephalography is a syndrome of idiopathic generalized epilepsy.MRS can quantitatively detect the concentration of neurometabolites noninvasively,and assess the metabolic changes in brain.Currently,studies of pathogenesis of JME are focused on the dysfunction of thalamo-cortical network and the neurometabolites and imbalance of Glutamate and γ-aminobutyric acid in the network are alterted.Epilepsy is associated with the imbalance of the ratio of excitatory and inhibitory amino acid,and seizures lead to neuronal lesions which result in altered concentration of neuron related metabolites.This article reviewed MRS studies of JME by combining material metabolism,neural structure and function.
Texte intégral:
1
Base de données:
WPRIM
Langue:
Zh
Journal:
Chinese Journal of Medical Imaging Technology
Année:
2017
Type de document:
Article