Research progress on reversion of multidrug resistance in tumor by cepharanthine / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
; (6): 1407-1410, 2019.
Article
de Zh
| WPRIM
| ID: wpr-800658
Bibliothèque responsable:
WPRO
ABSTRACT
This article reviews the related literature on the reversal of multi-drug resistance in tumors by cepharanthine, and summarizes the reversal effects and mechanisms of multi-drug resistance in different tumors such as leukemia, liver cancer, ovarian cancer, breast cancer, esophageal cancer and colon cancer. Its reversal effect on multi-drug resistance of tumors is the result of a multi-channel, multi-link combination. The main mechanism is to inhibit membrane transporter function, affect enzyme transfer system, inhibit anti-apoptotic pathway activation and anti-apoptotic protein expression.
Texte intégral:
1
Base de données:
WPRIM
Langue:
Zh
Journal:
International Journal of Traditional Chinese Medicine
Année:
2019
Type de document:
Article