Bioactive peptides from scorpion venoms: therapeutic scaffolds and pharmacological tools / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 19-35, 2023.
Article
de En
| WPRIM
| ID: wpr-971660
Bibliothèque responsable:
WPRO
ABSTRACT
Evolution and natural selection have endowed animal venoms, including scorpion venoms, with a wide range of pharmacological properties. Consequently, scorpions, their venoms, and/or their body parts have been used since time immemorial in traditional medicines, especially in Africa and Asia. With respect to their pharmacological potential, bioactive peptides from scorpion venoms have become an important source of scientific research. With the rapid increase in the characterization of various components from scorpion venoms, a large number of peptides are identified with an aim of combating a myriad of emerging global health problems. Moreover, some scorpion venom-derived peptides have been established as potential scaffolds helpful for drug development. In this review, we summarize the promising scorpion venoms-derived peptides as drug candidates. Accordingly, we highlight the data and knowledge needed for continuous characterization and development of additional natural peptides from scorpion venoms, as potential drugs that can treat related diseases.
Mots clés
Texte intégral:
1
Base de données:
WPRIM
Sujet principal:
Peptides
/
Venins de scorpion
/
Scorpions
/
Développement de médicament
/
Médecine traditionnelle
Limites:
Animals
Langue:
En
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Année:
2023
Type de document:
Article