Transcatheter Aortic Valve Replacement for Degenerated Transcatheter Aortic Valves: The TRANSIT International Project
Circ., cariovasc. interv. (Print)
; 14(6): 010440, June. 2021. graf, ilus, tab
Article
in En
| CONASS, SES-SP, SESSP-IDPCPROD, SES-SP
| ID: biblio-1352656
Responsible library:
BR79.1
ABSTRACT
BACKGROUND:
Transcatheter aortic valve replacement (TAVR) has determined a paradigm shift in the treatment of patients with severe aortic stenosis. However, the durability of bio prostheses is still a matter of concern, and little is known about the management of degenerated TAV. We sought to evaluate the outcomes of patients with a degenerated TAV treated by means of a second TAVR.METHODS:
The TRANSIT is an international registry that included cases of degenerated TAVR from 28 centers. Among around 40 000 patients treated with TAVR in the participating centers, 172 underwent a second TAVR 57 (33%) for a mainly stenotic degenerated TAV, 97 (56%) for a mainly regurgitant TAV, and 18 (11%) for a combined degeneration. Overall, the rate of New York Heart Association class III/IV at presentation was 73.5%.RESULTS:
Valve Academic Research Consortium 2 device success rate was 79%, as a consequence of residual gradient (14%) or regurgitation (7%). At 1 month, the overall mortality rate was 2.9%, while rates of new hospitalization and New York Heart Association class III/IV were 3.6% and 7%, respectively, without significant difference across the groups. At 1 year, the overall mortality rate was 10%, while rates of new hospitalization and New York Heart Association class III/IV were 7.6% and 5.8%, respectively, without significant difference across the groups. No cases of valve thrombosis were recorded.CONCLUSIONS:
Selected patients with a degenerated TAV may be safely and successfully treated by means of a second TAVR. This finding is of crucial importance for the adoption of the TAVR technology in a lower risk and younger population.
Full text:
1
Collection:
06-national
/
BR
Database:
CONASS
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SES-SP
/
SESSP-IDPCPROD
Main subject:
Aortic Valve Stenosis
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Prostheses and Implants
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Transcatheter Aortic Valve Replacement
Language:
En
Journal:
Circ., cariovasc. interv. (Print)
Year:
2021
Document type:
Article