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Sequencing of heparan sulfate proteoglycans: identification of variable and constant oligosaccharide regions in eight heparan sulfate proteoglycans of different origins
Tersariol, I. L. S; Ferreira, T. M. P. C; Medeiros, M. G. L; Porcianatto, M. A; Moraes, C. T; Abreu, L. R. D; Nader, H. B; Dietrich, C. P.
Rev. bras. pesqui. méd. biol ; Braz. j. med. biol. res;27(9): 2097-102, Sept. 1994. ilus
Article in En | LILACS | ID: lil-144462
Responsible library: BR1.1
ABSTRACT
The sequence of the disacharide units of eight heparan sulfate proteoglycans of different origins is described. All heparan sulfates contain 5 variable regions made of oligosaccharide blocks of disaccharides, namely GlcUA(1-4) GlcNAc, GlcUA(1-4)GlcNS, IdoUA (104)GlcNS) and monosaccharides (GlcNS, and GlcNS,65) at the non-reducing terminal. The N-acetylated region of the heparan sulfates is linked to the serine of the protein core through a trisaccharide of Xyl-Gal-Gal. Heparan sulfates differ from one another in terms of the number of disaccharides that compose each block
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Collection: 01-internacional Database: LILACS Main subject: Oligosaccharides / Proteoglycans / Heparitin Sulfate Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Braz. j. med. biol. res / Rev. bras. pesqui. méd. biol Journal subject: BIOLOGIA / MEDICINA Year: 1994 Document type: Article / Congress and conference Country of publication:
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Collection: 01-internacional Database: LILACS Main subject: Oligosaccharides / Proteoglycans / Heparitin Sulfate Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Braz. j. med. biol. res / Rev. bras. pesqui. méd. biol Journal subject: BIOLOGIA / MEDICINA Year: 1994 Document type: Article / Congress and conference Country of publication: