Urethral dysfunction due to alloxan-induced diabetes. Urodynamic evaluation and action of sildenafil citrate
Acta cir. bras
; 29(4): 274-279, abr. 2014. tab, graf
Article
in En
| LILACS
| ID: lil-706955
Responsible library:
BR1.1
ABSTRACT
To evaluate the effect of diabetes mellitus and of sildenafil citrate on female urethral function. Twenty nine female rats were divided into four groups G1 - (n=9), normal rats; G2 - (n=6), normal rats treated with sildenafil citrate; G3 - (n=9) rats with alloxan-induced diabetes; G4 - (n=5) rats with alloxan-induced diabetes treated with sildenafil citrate. Under anesthesia, urodynamic evaluation was performed by cystometry and urethral pressure simultaneously. A significant increase in urethral pressure was observed during micturition. Sildenafil citrate can partially reduced urethral pressure in diabetic female rats.
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Urethra
/
Urinary Bladder
/
Alloxanum
/
Diabetes Complications
Limits:
Animals
Language:
En
Journal:
Acta cir. bras
Journal subject:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2014
Document type:
Article
Affiliation country: