Interaction of C17orf25 with ADP-ribose pyrophosphatase NUDT9 detected via yeast two-hybrid method.
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
; 35(8): 747-51, 2003 Aug.
Article
in En
| MEDLINE
| ID: mdl-12897971
ABSTRACT
The gene C17orf25 was isolated from the liver by RACE PCR. nudt9 gene was screened by yeast two-hybrid method in MatchMaker human HeLa cDNA library. NUDT9 is an enzyme that has pyrophosphatase activity with ADP-ribose as its substrate. Fusion expression of C17orf25 and GFP and computer analysis showed that C17orf25 was probably located in mitochondria. Furthermore, C17orf25 may suppress the cell growth by interaction with NUDT9.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pyrophosphatases
/
Proteins
/
Two-Hybrid System Techniques
Limits:
Humans
Language:
En
Journal:
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
Year:
2003
Document type:
Article
Affiliation country: