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4,6-Disubstituted 2,2-dimethylchromans structurally related to the K(ATP) channel opener cromakalim: design, synthesis, and effect on insulin release and vascular tone.
Sebille, Sophie; de Tullio, Pascal; Becker, Bénédicte; Antoine, Marie-Hélène; Boverie, Stéphane; Pirotte, Bernard; Lebrun, Philippe.
Affiliation
  • Sebille S; Natural and Synthetic Drugs Research Center, Department of Medicinal Chemistry, Université de Liège, 1 av. de l'Hôpital, tour 4 (+5) Sart-Tilman, B-4000 Liège, Belgium. Sophie.Sebille@ulg.ac.be
J Med Chem ; 48(2): 614-21, 2005 Jan 27.
Article in En | MEDLINE | ID: mdl-15658874
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Collection: 01-internacional Database: MEDLINE Main subject: Vasodilator Agents / Potassium Channels / Ion Channel Gating / Chromans / Islets of Langerhans / Cromakalim / Insulin / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2005 Document type: Article Affiliation country: Country of publication:
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Collection: 01-internacional Database: MEDLINE Main subject: Vasodilator Agents / Potassium Channels / Ion Channel Gating / Chromans / Islets of Langerhans / Cromakalim / Insulin / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2005 Document type: Article Affiliation country: Country of publication: