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Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation.
Nabbe, Karin C A M; van Lent, Peter L E M; Holthuysen, Astrid E M; Sloëtjes, Annet W; Koch, Alisa E; Radstake, Timothy R D J; van den Berg, Wim B.
Affiliation
  • Nabbe KC; Department of Experimental Rheumatology and Advanced Therapeutics, University Medical Center Nijmegen, Nijmegen, The Netherlands. k.nabbe@reuma.umcn.nl
Arthritis Res Ther ; 7(2): R392-401, 2005.
Article in En | MEDLINE | ID: mdl-15743487
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Peptide Fragments / Arthritis, Experimental / Genetic Therapy / Cartilage, Articular / Immune Complex Diseases / Interleukin-13 / Chondrocytes / Matrix Metalloproteinases / Extracellular Matrix Limits: Animals Language: En Journal: Arthritis Res Ther Journal subject: REUMATOLOGIA Year: 2005 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Peptide Fragments / Arthritis, Experimental / Genetic Therapy / Cartilage, Articular / Immune Complex Diseases / Interleukin-13 / Chondrocytes / Matrix Metalloproteinases / Extracellular Matrix Limits: Animals Language: En Journal: Arthritis Res Ther Journal subject: REUMATOLOGIA Year: 2005 Document type: Article Affiliation country: Country of publication: