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Gene targeting using a promoterless gene trap vector ("targeted trapping") is an efficient method to mutate a large fraction of genes.
Friedel, Roland H; Plump, Andrew; Lu, Xiaowei; Spilker, Kerri; Jolicoeur, Christine; Wong, Karen; Venkatesh, Tadmiri R; Yaron, Avraham; Hynes, Mary; Chen, Bin; Okada, Ami; McConnell, Susan K; Rayburn, Helen; Tessier-Lavigne, Marc.
Affiliation
  • Friedel RH; Department of Biological Sciences, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Proc Natl Acad Sci U S A ; 102(37): 13188-93, 2005 Sep 13.
Article in En | MEDLINE | ID: mdl-16129827
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mutagenesis, Insertional / Gene Targeting / Genetic Vectors Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2005 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mutagenesis, Insertional / Gene Targeting / Genetic Vectors Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2005 Document type: Article Affiliation country: Country of publication: