Arrestins/physiology; Receptors, Thyrotropin-Releasing Hormone/physiology; Alkaline Phosphatase/metabolism; Animals; Arrestins/chemistry; Arrestins/metabolism; CHO Cells; COS Cells; Calcium Channels/metabolism; Cell Line; Cell Membrane/metabolism; Chlorocebus aethiops; Cricetinae; DNA, Complementary/metabolism; Dose-Response Relationship, Drug; Endocytosis; Fibroblasts/metabolism; G-Protein-Coupled Receptor Kinase 2; GTP-Binding Protein alpha Subunits, Gq-G11/metabolism; GTP-Binding Proteins/metabolism; Glycosylation; Green Fluorescent Proteins/metabolism; Immunoblotting; Immunoglobulin G/chemistry; Immunoprecipitation; Inositol 1,4,5-Trisphosphate/metabolism; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates/chemistry; Inositol Phosphates/metabolism; Kinetics; Mice; Mice, Knockout; Mutation; Phosphates/chemistry; Phosphorylation; Plasmids/metabolism; Protein Binding; Protein Kinase C/antagonists & inhibitors; Protein Kinase C/metabolism; Protein Structure, Tertiary; Protein Transport; Receptors, Cytoplasmic and Nuclear/metabolism; Receptors, Thyrotropin-Releasing Hormone/chemistry; Sucrose/chemistry; Sucrose/pharmacology; Time Factors; Transfection; beta-Adrenergic Receptor Kinases/metabolism; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins