An inter-gender effect on ethanol drinking in rats: proximal females increase ethanol drinking in males.
Pharmacol Biochem Behav
; 83(2): 307-13, 2006 Feb.
Article
in En
| MEDLINE
| ID: mdl-16563476
ABSTRACT
Three groups of male Long-Evans hooded rats were assessed for effects of social opportunity on drinking of ethanol or water. The ethanol/female group received intermittent presentations of a sipper containing ethanol that was followed by 15 s of social interaction opportunity with a female rat. The ethanol/male group received similar training except the social interaction opportunity was with a male rat. The water/female group received training similar to the ethanol/female group except that the sipper contained water. For the ethanol groups, the concentration of ethanol [3%, 4%, 6%, 8% and 10% (vol/vol)] in the sipper was increased across sessions. With 10% ethanol in the sipper, social opportunity with females induced more drinking and ethanol intake than did social opportunity with males. Social opportunity with females induced more intake of ethanol than water. Post-session plasma samples revealed social opportunity with females induced higher corticosterone and testosterone levels than did social opportunity with males, irrespective of the sipper fluid. This study documents, for the first time, an inter-gender effect on ethanol drinking in rats.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Behavior, Animal
/
Alcohol Drinking
Aspects:
Determinantes_sociais_saude
Limits:
Animals
Language:
En
Journal:
Pharmacol Biochem Behav
Year:
2006
Document type:
Article
Affiliation country:
Publication country:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA