Manipulation of the human genome in human embryonic stem cells.
Stem Cell Rev
; 1(2): 145-50, 2005.
Article
in En
| MEDLINE
| ID: mdl-17142849
ABSTRACT
Human embryonic stem cells (HESCs) have a tremendous clinical and scientific importance since they may serve as a cell source for transplantation and as a system for the study of human development and disease. The genetic engineering of HESCs has become instrumental in achieving these goals. Here we discuss various methodologies to genetically manipulate HESCs and propose a variety of applications of the modified cells in basic and applied research.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Genome, Human
/
Embryonic Stem Cells
Limits:
Animals
/
Humans
Language:
En
Journal:
Stem Cell Rev
Year:
2005
Document type:
Article
Affiliation country: