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Novel tricyclic compounds having acetylene groups at C-8a and cyano enones in rings A and C: highly potent anti-inflammatory and cytoprotective agents.
Honda, Tadashi; Sundararajan, Chitra; Yoshizawa, Hidenori; Su, Xiaobo; Honda, Yukiko; Liby, Karen T; Sporn, Michael B; Gribble, Gordon W.
Affiliation
  • Honda T; Department of Chemistry, Dartmouth College, 6128 Burke Laboratory, Hanover, New Hampshire 03755, USA. th9@dartmouth.edu
J Med Chem ; 50(8): 1731-4, 2007 Apr 19.
Article in En | MEDLINE | ID: mdl-17367124
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oleanolic Acid / Anti-Inflammatory Agents, Non-Steroidal / Alkynes / Heterocyclic Compounds, 3-Ring / Antineoplastic Agents / Nitriles Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2007 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oleanolic Acid / Anti-Inflammatory Agents, Non-Steroidal / Alkynes / Heterocyclic Compounds, 3-Ring / Antineoplastic Agents / Nitriles Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2007 Document type: Article Affiliation country: Country of publication: