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Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir.
Jiang, Zibin; Pore, Nabendu; Cerniglia, George J; Mick, Rosemarie; Georgescu, Maria-Magdelena; Bernhard, Eric J; Hahn, Stephen M; Gupta, Anjali K; Maity, Amit.
Affiliation
  • Jiang Z; Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
Cancer Res ; 67(9): 4467-73, 2007 May 01.
Article in En | MEDLINE | ID: mdl-17483362
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Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Brain Neoplasms / Glioblastoma / Antineoplastic Agents, Alkylating / Nelfinavir / Dacarbazine / PTEN Phosphohydrolase Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2007 Document type: Article Affiliation country: Country of publication:
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Collection: 01-internacional Database: MEDLINE Main subject: Protease Inhibitors / Brain Neoplasms / Glioblastoma / Antineoplastic Agents, Alkylating / Nelfinavir / Dacarbazine / PTEN Phosphohydrolase Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2007 Document type: Article Affiliation country: Country of publication: