Neuromyelitis optica (Devic's disease) in a patient with syphilis.
Mult Scler
; 14(2): 268-71, 2008 Mar.
Article
in En
| MEDLINE
| ID: mdl-17986508
ABSTRACT
The patient initially presented with bilateral optic neuritis and periventricular cranial MRI abnormalities in the context of syphilis. Blood was positive but cerebrospinal fluid testing was negative for specific syphilis markers and he was oligoclonal cerebrospinal fluid (CSF) band negative. He initially responded well to penicillin and corticosteriod treatment, but went on to develop the clinical syndrome of neuromyelitis optica (NMO). Testing for the presence of the serum autoantibody for aquaporin-4 was negative. This patient appears to represent another case of post-infectious NMO. Possible pathogenesis of this post-syphilis NMO syndrome in the patient is discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neuromyelitis Optica
/
Neurosyphilis
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Mult Scler
Journal subject:
NEUROLOGIA
Year:
2008
Document type:
Article
Affiliation country: