Antifungal susceptibility against yeasts isolated from pediatric oncology patients.
Med Mycol
; 46(4): 337-43, 2008 Jun.
Article
in En
| MEDLINE
| ID: mdl-18415840
ABSTRACT
Yeast infections cause morbidity in children with cancer and we evaluated species distribution and antifungal susceptibilities of the etiologic agents in this group. Specimens from 58 children yielded 64 cultures positive for yeasts. Central venous catheters were present in 56 (97%) of the children and neutrophil counts were <500 cells/ml3 in 34% of the patients. Twenty-two (38%) had received recent antifungal treatment, with 15 (25%) receiving fluconazole (FLU) prophylaxis. The Candida isolates recovered from four (27%) of the children on FLU prophylaxis, were resistant to this drug. Candida albicans isolates were susceptible to 100% of antifungals tested, whereas non-C. albicans Candida spp. were variable in their susceptibility patterns. FLU prophylaxis minimally affected susceptibility.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Candida
/
Drug Resistance, Fungal
/
Antifungal Agents
/
Neoplasms
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Humans
/
Infant
/
Newborn
Language:
En
Journal:
Med Mycol
Journal subject:
MEDICINA VETERINARIA
/
MICROBIOLOGIA
Year:
2008
Document type:
Article
Affiliation country: