[Vagus nerve stimulation for the treatment of refractory epilepsy]. / Stimulation chronique du nerf vague dans le traitement del'épilepsie pharmacorésistante.
Neurochirurgie
; 54(3): 332-9, 2008 May.
Article
in Fr
| MEDLINE
| ID: mdl-18423773
ABSTRACT
Proposed as an additive symptomatic treatment of refractory epilepsy, vagus nerve stimulation (VNS) has proven to be effective and well-tolerated in patients presenting with refractory epilepsy for whom cortical resection is not indicated. After two years of treatment, the overall reduction of seizure frequency averaged 40%. In 50% of the patients, the frequency of seizures decreased by at least 50%. Moreover, even in absence of a significant reduction of seizures, patients who undergo this treatment reported an improvement in their quality of life. Economic surveys also demonstrate a favorable impact of VNS on the management of refractory epilepsy. Since 1988, 65,000 patients with refractory epilepsy throughout the world have been treated by VNS for this indication (1000 in France). The surgical implantation technique used in our department, the effects of vagus nerve stimulation reported in the literature, and our experience with a cohort of 70 patients with refractory epilepsy who received implants over the last 10 years are described.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vagus Nerve
/
Electric Stimulation Therapy
/
Epilepsy
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Fr
Journal:
Neurochirurgie
Year:
2008
Document type:
Article
Affiliation country: