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The hydrophobic tunnel present in LOX-1 is essential for oxidized LDL recognition and binding.
Francone, Omar L; Tu, Meihua; Royer, Lori J; Zhu, Jian; Stevens, Kimberly; Oleynek, Joseph J; Lin, Zhiwu; Shelley, Lorraine; Sand, Thomas; Luo, Yi; Kane, Christopher D.
Affiliation
  • Francone OL; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340. Electronic address: omar.l.francone@pfizer.com.
  • Tu M; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Royer LJ; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Zhu J; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Stevens K; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Oleynek JJ; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Lin Z; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Shelley L; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Sand T; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Luo Y; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
  • Kane CD; Department of Atherosclerosis Biology, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340.
J Lipid Res ; 50(3): 546-555, 2009 Mar.
Article in En | MEDLINE | ID: mdl-18845619
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scavenger Receptors, Class E / Lipoproteins, LDL Limits: Animals / Humans Language: En Journal: J Lipid Res Year: 2009 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Scavenger Receptors, Class E / Lipoproteins, LDL Limits: Animals / Humans Language: En Journal: J Lipid Res Year: 2009 Document type: Article Country of publication: