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The Marburg I variant (G534E) of the factor VII-activating protease determines liver fibrosis in hepatitis C infection by reduced proteolysis of platelet-derived growth factor BB.
Wasmuth, Hermann E; Tag, Carmen G; Van de Leur, Eddie; Hellerbrand, Claus; Mueller, Tobias; Berg, Thomas; Puhl, Gero; Neuhaus, Peter; Samuel, Didier; Trautwein, Christian; Kanse, Sandip M; Weiskirchen, Ralf.
Affiliation
  • Wasmuth HE; Department of Internal Medicine III, University Hospital Aachen, Aachen, Germany.
Hepatology ; 49(3): 775-80, 2009 Mar.
Article in En | MEDLINE | ID: mdl-19105210
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Platelet-Derived Growth Factor / Serine Endopeptidases / Hepatitis C / Liver Cirrhosis Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Hepatology Year: 2009 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Platelet-Derived Growth Factor / Serine Endopeptidases / Hepatitis C / Liver Cirrhosis Type of study: Etiology_studies / Observational_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Hepatology Year: 2009 Document type: Article Affiliation country: Country of publication: