Immunoglobulin M 'Flare' after rituximab-associated acute tubular necrosis in Waldenström's macroglobulinemia.
Int J Hematol
; 89(2): 218-222, 2009 Mar.
Article
in En
| MEDLINE
| ID: mdl-19156501
ABSTRACT
Waldenström's macroglobulinemia (WM) is a low-grade lymphoplasmacytic lymphoma characterized by a circulating monoclonal IgM. Renal involvement in classical cases of WM is rare, and the pathological hallmark finding in the renal biopsy specimen is a thrombotic microangiopathy. We report the case of a 69-year-old man with the diagnosis of WM for 3 months before he presented with acute renal failure (ARF). A renal biopsy performed suggested the diagnosis of acute tubular necrosis. The diagnosis of ARF related to IgM flare after Rituximab therapy was made.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Immunoglobulin M
/
Waldenstrom Macroglobulinemia
/
Acute Kidney Injury
/
Kidney Tubules
/
Antibodies, Monoclonal
Type of study:
Risk_factors_studies
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
Int J Hematol
Journal subject:
HEMATOLOGIA
Year:
2009
Document type:
Article
Affiliation country: