Your browser doesn't support javascript.
loading
Calcium-independent membrane damage by venom phospholipases A2.
de Oliveira, A H C; Aragão, E A; Sá, J M; Chioato, L; Bugs-Bortoleto, R; Ruller, R; Ferreira, T L; Ward, R J.
Affiliation
  • de Oliveira AH; Departamento de Química, FFCLRP-USP, Universidade de São Paulo, Brazil.
Protein Pept Lett ; 16(8): 877-86, 2009.
Article in En | MEDLINE | ID: mdl-19689413
ABSTRACT
Many snake venom phospholipase A(2)s (vPLA(2)s) present biological effects that are independent of hydrolytic activity. Here we review the evidence for the calcium-independent membrane damaging activity of vPLA(2)s, the possible relevance of this activity on their biological effects, and models for the mechanism of membrane permeabilization by these proteins.
Subject(s)
Search on Google
Add to My VHL
Print
XML
PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Snake Venoms / Snakes / Phospholipases A2 Limits: Animals / Humans Language: En Journal: Protein Pept Lett Journal subject: BIOQUIMICA Year: 2009 Document type: Article Affiliation country:
Search on Google
Add to My VHL
Print
XML
PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Snake Venoms / Snakes / Phospholipases A2 Limits: Animals / Humans Language: En Journal: Protein Pept Lett Journal subject: BIOQUIMICA Year: 2009 Document type: Article Affiliation country: