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Design, synthesis, and evaluation of 2-methyl- and 2-amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as ring-constrained 2-anilino-4-(thiazol-5-yl)pyrimidine cyclin-dependent kinase inhibitors.
McIntyre, Neil A; McInnes, Campbell; Griffiths, Gary; Barnett, Anna L; Kontopidis, George; Slawin, Alexandra M Z; Jackson, Wayne; Thomas, Mark; Zheleva, Daniella I; Wang, Shudong; Blake, David G; Westwood, Nicholas J; Fischer, Peter M.
Affiliation
  • McIntyre NA; School of Chemistry and Biomedical Sciences Research Complex, University of St. Andrews, North Haugh, St Andrews, Fife KY16 9ST, UK.
J Med Chem ; 53(5): 2136-45, 2010 Mar 11.
Article in En | MEDLINE | ID: mdl-20146435
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Cyclin-Dependent Kinases / Protein Kinase Inhibitors / Aminoquinolines Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2010 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Cyclin-Dependent Kinases / Protein Kinase Inhibitors / Aminoquinolines Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2010 Document type: Article Affiliation country: