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Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE*3 Leiden and low-density lipoprotein receptor-/- mice.
Bietrix, Florence; Lombardo, Elisa; van Roomen, Cindy P A A; Ottenhoff, Roelof; Vos, Mariska; Rensen, Patrick C N; Verhoeven, Arthur J; Aerts, Johannes M; Groen, Albert K.
Affiliation
  • Bietrix F; Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, the Netherlands.
Arterioscler Thromb Vasc Biol ; 30(5): 931-7, 2010 May.
Article in En | MEDLINE | ID: mdl-20167657
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Adamantane / Receptors, LDL / Glycosphingolipids / Cholesterol / 1-Deoxynojirimycin / Enzyme Inhibitors / Atherosclerosis / Glucosyltransferases Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2010 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Adamantane / Receptors, LDL / Glycosphingolipids / Cholesterol / 1-Deoxynojirimycin / Enzyme Inhibitors / Atherosclerosis / Glucosyltransferases Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2010 Document type: Article Affiliation country: Country of publication: