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Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.
Tinsley, Jonathon M; Fairclough, Rebecca J; Storer, Richard; Wilkes, Fraser J; Potter, Allyson C; Squire, Sarah E; Powell, Dave S; Cozzoli, Anna; Capogrosso, Roberta F; Lambert, Adam; Wilson, Francis X; Wren, Stephen P; De Luca, Annamaria; Davies, Kay E.
Affiliation
  • Tinsley JM; Summit plc, Abingdon, United Kingdom. Jon.Tinsley@summitplc.com
PLoS One ; 6(5): e19189, 2011 May 06.
Article in En | MEDLINE | ID: mdl-21573153
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Utrophin / Muscular Dystrophy, Animal Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Utrophin / Muscular Dystrophy, Animal Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: Country of publication: