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Biphenyl/diphenyl ether renin inhibitors: filling the S1 pocket of renin via the S3 pocket.
Yuan, Jing; Simpson, Robert D; Zhao, Wei; Tice, Colin M; Xu, Zhenrong; Cacatian, Salvacion; Jia, Lanqi; Flaherty, Patrick T; Guo, Joan; Ishchenko, Alexey; Wu, Zhongren; McKeever, Brian M; Scott, Boyd B; Bukhtiyarov, Yuri; Berbaum, Jennifer; Panemangalore, Reshma; Bentley, Ross; Doe, Christopher P; Harrison, Richard K; McGeehan, Gerard M; Singh, Suresh B; Dillard, Lawrence W; Baldwin, John J; Claremon, David A.
Affiliation
  • Yuan J; Vitae Pharmaceuticals, 502 West Office Center Drive, Fort Washington, PA 19034, USA. jyuan@vitaerx.com
Bioorg Med Chem Lett ; 21(16): 4836-43, 2011 Aug 15.
Article in En | MEDLINE | ID: mdl-21741239
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenyl Ethers / Renin / Enzyme Inhibitors / Antihypertensive Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenyl Ethers / Renin / Enzyme Inhibitors / Antihypertensive Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Document type: Article Affiliation country: Country of publication: