Discovery, synthesis, and structure-activity relationship of 6-aminomethyl-7,8-dihydronaphthalenes as human melanin-concentrating hormone receptor 1 antagonists.

Kamata, Makoto; Yamashita, Toshiro; Imaeda, Toshihiro; Tanaka, Toshio; Terauchi, Jun; Miyamoto, Maki; Ora, Taiichi; Tawada, Michiko; Endo, Satoshi; Takekawa, Shiro; Asami, Asano; Suzuki, Nobuhiro; Nagisa, Yasutaka; Nakano, Yoshihide; Watanabe, Kaoru; Ogino, Hitomi; Kato, Koki; Kato, Kaneyoshi; Ishihara, Yuji

Kamata, Makoto; Yamashita, Toshiro; Imaeda, Toshihiro; Tanaka, Toshio; Terauchi, Jun; Miyamoto, Maki; Ora, Taiichi; Tawada, Michiko; Endo, Satoshi; Takekawa, Shiro; Asami, Asano; Suzuki, Nobuhiro; Nagisa, Yasutaka; Nakano, Yoshihide; Watanabe, Kaoru; Ogino, Hitomi; Kato, Koki; Kato, Kaneyoshi; Ishihara, Yuji.

Affiliation

Kamata M; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 17-85 Jusohonmachi, 2-Chome, Yodogawa-ku, Osaka 532-8686, Japan. Kamata_Makoto@takeda.co.jp

Bioorg Med Chem ; 19(18): 5539-52, 2011 Sep 15.

Article in En | MEDLINE | ID: mdl-21856163

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetrahydronaphthalenes / Receptors, Somatostatin / Drug Discovery Limits: Animals / Female / Humans / Male Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Document type: Article Affiliation country:

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