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Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors.
Gurney, Austin; Axelrod, Fumiko; Bond, Christopher J; Cain, Jennifer; Chartier, Cecile; Donigan, Lucas; Fischer, Marcus; Chaudhari, Aurélie; Ji, May; Kapoun, Ann M; Lam, Andrew; Lazetic, Sasha; Ma, Shirley; Mitra, Satyajit; Park, In-Kyung; Pickell, Kellie; Sato, Aaron; Satyal, Sanjeev; Stroud, Michelle; Tran, Hoang; Yen, Wan-Ching; Lewicki, John; Hoey, Timothy.
Affiliation
  • Gurney A; OncoMed Pharmaceuticals, Redwood City, CA 94063, USA. austin.gurney@oncomed.com
Proc Natl Acad Sci U S A ; 109(29): 11717-22, 2012 Jul 17.
Article in En | MEDLINE | ID: mdl-22753465
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frizzled Receptors / Wnt Signaling Pathway / Antibodies, Monoclonal / Neoplasms / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2012 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Frizzled Receptors / Wnt Signaling Pathway / Antibodies, Monoclonal / Neoplasms / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2012 Document type: Article Affiliation country: Country of publication: