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AT13148 is a novel, oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity.
Yap, Timothy A; Walton, Mike I; Grimshaw, Kyla M; Te Poele, Robert H; Eve, Paul D; Valenti, Melanie R; de Haven Brandon, Alexis K; Martins, Vanessa; Zetterlund, Anna; Heaton, Simon P; Heinzmann, Kathrin; Jones, Paul S; Feltell, Ruth E; Reule, Matthias; Woodhead, Steven J; Davies, Thomas G; Lyons, John F; Raynaud, Florence I; Eccles, Suzanne A; Workman, Paul; Thompson, Neil T; Garrett, Michelle D.
Affiliation
  • Yap TA; Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, Sutton, United Kingdom.
Clin Cancer Res ; 18(14): 3912-23, 2012 Jul 15.
Article in En | MEDLINE | ID: mdl-22781553
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Phosphatidylinositol 3-Kinase / Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2012 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Phosphatidylinositol 3-Kinase / Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2012 Document type: Article Affiliation country: Country of publication: