N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11ß-hydroxysteroid dehydrogenase type 1: strategies to eliminate reactive metabolites.

Nair, Sajiv K; Matthews, Jean J; Cripps, Stephan J; Cheng, Hengmiao; Hoffman, Jacqui E; Smith, Christopher; Kupchinsky, Stanley; Siu, Michael; Taylor, Wendy D; Wang, Yong; Johnson, Theodore O; Dress, Klaus R; Edwards, Martin P; Zhou, Sue; Hosea, Natilie A; Lapaglia, Amy; Kang, Ping; Castro, Arturo; Ermolieff, Jacques; Fanjul, Andrea; Vogel, Jennifer E; Rejto, Paul; Dalvie, Deepak

Nair, Sajiv K; Matthews, Jean J; Cripps, Stephan J; Cheng, Hengmiao; Hoffman, Jacqui E; Smith, Christopher; Kupchinsky, Stanley; Siu, Michael; Taylor, Wendy D; Wang, Yong; Johnson, Theodore O; Dress, Klaus R; Edwards, Martin P; Zhou, Sue; Hosea, Natilie A; Lapaglia, Amy; Kang, Ping; Castro, Arturo; Ermolieff, Jacques; Fanjul, Andrea; Vogel, Jennifer E; Rejto, Paul; Dalvie, Deepak.

Affiliation

Nair SK; Medicinal Chemistry, Pfizer Global R&D, San Diego, CA 92121, USA. sajiv.k.nair@pfizer.com

Bioorg Med Chem Lett ; 23(8): 2344-8, 2013 Apr 15.

Article in En | MEDLINE | ID: mdl-23489629

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / 11-beta-Hydroxysteroid Dehydrogenase Type 1 / Aminopyridines Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2013 Document type: Article Affiliation country: Country of publication:

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