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Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.
Hopkins, Seth C; Heffernan, Michele L R; Saraswat, Lakshmi D; Bowen, Carrie A; Melnick, Laurence; Hardy, Larry W; Orsini, Michael A; Allen, Michael S; Koch, Patrick; Spear, Kerry L; Foglesong, Robert J; Soukri, Mustapha; Chytil, Milan; Fang, Q Kevin; Jones, Steven W; Varney, Mark A; Panatier, Aude; Oliet, Stephane H R; Pollegioni, Loredano; Piubelli, Luciano; Molla, Gianluca; Nardini, Marco; Large, Thomas H.
Affiliation
  • Hopkins SC; Sunovion Pharmaceuticals Inc., Marlborough, Massachusetts 01752, United States. seth.hopkins@sunovion.com
J Med Chem ; 56(9): 3710-24, 2013 May 09.
Article in En | MEDLINE | ID: mdl-23631755
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: D-Amino-Acid Oxidase / Enzyme Inhibitors / Small Molecule Libraries Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: D-Amino-Acid Oxidase / Enzyme Inhibitors / Small Molecule Libraries Limits: Animals / Humans / Male Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: Country of publication: