Changes of choroidal thickness, intraocular pressure and other optical coherence tomographic parameters after haemodialysis.
Clin Exp Optom
; 96(5): 494-9, 2013 Sep.
Article
in En
| MEDLINE
| ID: mdl-23638771
ABSTRACT
BACKGROUND:
The aim was to evaluate changes in choroidal thickness, intraocular pressure (IOP) and other parameters of optical coherence tomography, such as central foveal thickness (CFT), macular volume, peripapillary retinal nerve fibre layer (RNFL) thickness after haemodialysis (HD).METHODS:
Thirty-four eyes of 34 chronic renal failure patients (9 eyes with diabetic patients) who underwent haemodialysis in the Dialysis Unit of Gangneung Asan Hospital were included. CFT, macular volume, peripapillary RNFL and choroidal thickness were measured before and after haemodialysis by optical coherence tomography (OCT, Spectralis; Heidelberg Engineering). Changes in the IOP were evaluated with Goldmann applanation tonometry before and after haemodialysis.RESULTS:
The average choroidal thickness decreased significantly, from 233.1 ± 77.5 µm to 219.1 ± 76.8 µm (paired t-test, p < 0.001). This change correlated with the amount of body weight lost (Pearson's correlation coefficient = 0.348, p = 0.044). The mean IOP decreased from 15.1 ± 2.6 mmHg to 13.9 ± 2.2 mmHg after haemodialysis (paired t-test, p = 0.03). The change in macular volume and the small decrease in CFT (214.0 ± 21.0 µm to 213.8 ± 21.8 µm) were not significant. The measured overall change in RNFL thickness from 93.6 ± 15.5 µm to 94.7 ± 14.6 µm was not significant.CONCLUSIONS:
Haemodialysis can affect various ocular parameters, particularly choroidal thickness and IOP.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Choroid Diseases
/
Choroid
/
Renal Dialysis
/
Tomography, Optical Coherence
/
Intraocular Pressure
/
Kidney Failure, Chronic
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Exp Optom
Journal subject:
OPTOMETRIA
Year:
2013
Document type:
Article
Affiliation country: