Vitamin D and immune function.
Nutrients
; 5(7): 2502-21, 2013 Jul 05.
Article
in En
| MEDLINE
| ID: mdl-23857223
Vitamin D metabolizing enzymes and vitamin D receptors are present in many cell types including various immune cells such as antigen-presenting-cells, T cells, B cells and monocytes. In vitro data show that, in addition to modulating innate immune cells, vitamin D also promotes a more tolerogenic immunological status. In vivo data from animals and from human vitamin D supplementation studies have shown beneficial effects of vitamin D on immune function, in particular in the context of autoimmunity. In this review, currently available data are summarized to give an overview of the effects of vitamin D on the immune system in general and on the regulation of inflammatory responses, as well as regulatory mechanisms connected to autoimmune diseases particularly in type 1 diabetes mellitus.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vitamin D
/
Dietary Supplements
/
Immune System
Type of study:
Clinical_trials
Limits:
Animals
/
Humans
Language:
En
Journal:
Nutrients
Year:
2013
Document type:
Article
Affiliation country:
Country of publication: