Linear and micronodular neuroendocrine cell hyperplasia in an ovarian mucinous cystadenoma.
Pathol Res Pract
; 209(10): 670-3, 2013 Oct.
Article
in En
| MEDLINE
| ID: mdl-23891137
ABSTRACT
We report a rare case of an ovarian mucinous cystadenoma in which there were peculiar neuroendocrine micronests composed of gastrin-immunoreactive cells. There was no clinical evidence of hypergastrinemia. The mucinous component of the neoplasm was represented by columnar cells mostly expressing a gastric phenotype with MUC5AC and claudin 18 positivity, which was consistent with the presence of interspersed gastrin cells. The tumoral stroma displayed areas of luteinization with cells intensely positive for α-inhibin, MART-1 and calretinin.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ovarian Neoplasms
/
Cystadenoma, Mucinous
/
Neuroendocrine Cells
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Pathol Res Pract
Year:
2013
Document type:
Article
Affiliation country: