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Selective strong synergism of Ruxolitinib and second generation tyrosine kinase inhibitors to overcome bone marrow stroma related drug resistance in chronic myelogenous leukemia.
Quintarelli, Concetta; De Angelis, Biagio; Errichiello, Santa; Caruso, Simona; Esposito, Nicola; Colavita, Irene; Raia, Maddalena; Pagliuca, Simona; Pugliese, Novella; Risitano, Antonio M; Picardi, Marco; Luciano, Luigia; Saglio, Giuseppe; Martinelli, Giovanni; Pane, Fabrizio.
Affiliation
  • Quintarelli C; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy. Electronic address: concetta.quintarelli@unina.it.
  • De Angelis B; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Errichiello S; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Caruso S; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Esposito N; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Colavita I; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Raia M; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Pagliuca S; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Pugliese N; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Risitano AM; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Picardi M; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
  • Luciano L; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy.
  • Saglio G; Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.
  • Martinelli G; Department of Haematology/Oncology "L. e A. Seràgnoli", University of Bologna, Bologna, Italy.
  • Pane F; Dipartimento di Medicina Clinica e Chirurgia, University of Naples Federico II, Italy; CEINGE Biotecnologie Avanzate, Napoli, Italy.
Leuk Res ; 38(2): 236-42, 2014 Feb.
Article in En | MEDLINE | ID: mdl-24280282
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Bone Marrow / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Antineoplastic Combined Chemotherapy Protocols / Drug Resistance, Neoplasm / Protein Kinase Inhibitors Limits: Humans Language: En Journal: Leuk Res Year: 2014 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Bone Marrow / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Antineoplastic Combined Chemotherapy Protocols / Drug Resistance, Neoplasm / Protein Kinase Inhibitors Limits: Humans Language: En Journal: Leuk Res Year: 2014 Document type: Article