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Effective intravenous therapy for neurodegenerative disease with a therapeutic enzyme and a peptide that mediates delivery to the brain.
Meng, Yu; Sohar, Istvan; Sleat, David E; Richardson, Jason R; Reuhl, Kenneth R; Jenkins, Robert B; Sarkar, Gobinda; Lobel, Peter.
Affiliation
  • Meng Y; Center for Advanced Biotechnology and Medicine, Piscataway, New Jersey, USA.
  • Sohar I; Center for Advanced Biotechnology and Medicine, Piscataway, New Jersey, USA.
  • Sleat DE; Center for Advanced Biotechnology and Medicine, Piscataway, New Jersey, USA; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA.
  • Richardson JR; Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA.
  • Reuhl KR; Department of Pharmacology & Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, USA.
  • Jenkins RB; Department of Experimental Pathology, Mayo Clinic, Rochester, Minnesota, USA.
  • Sarkar G; Department of Experimental Pathology, Mayo Clinic, Rochester, Minnesota, USA; Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, USA.
  • Lobel P; Center for Advanced Biotechnology and Medicine, Piscataway, New Jersey, USA; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, New Jersey, USA. Electronic address: lobel@cabm.rutgers.edu.
Mol Ther ; 22(3): 547-553, 2014 Mar.
Article in En | MEDLINE | ID: mdl-24394185
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Peptides / Blood-Brain Barrier / Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Serine Proteases / Aminopeptidases / Neuronal Ceroid-Lipofuscinoses Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2014 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Peptides / Blood-Brain Barrier / Dipeptidyl-Peptidases and Tripeptidyl-Peptidases / Serine Proteases / Aminopeptidases / Neuronal Ceroid-Lipofuscinoses Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2014 Document type: Article Affiliation country: Country of publication: