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IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances.
Gostissa, Monica; Schwer, Bjoern; Chang, Amelia; Dong, Junchao; Meyers, Robin M; Marecki, Gregory T; Choi, Vivian W; Chiarle, Roberto; Zarrin, Ali A; Alt, Frederick W.
Affiliation
  • Gostissa M; Howard Hughes Medical Institute, Program in Cellular and Molecular Medicine, Boston Children's Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02115.
Proc Natl Acad Sci U S A ; 111(7): 2644-9, 2014 Feb 18.
Article in En | MEDLINE | ID: mdl-24550291
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / B-Lymphocytes / Immunoglobulin Heavy Chains / Immunoglobulin Class Switching / DNA Repair / DNA Breaks, Double-Stranded / Neoplasms Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / B-Lymphocytes / Immunoglobulin Heavy Chains / Immunoglobulin Class Switching / DNA Repair / DNA Breaks, Double-Stranded / Neoplasms Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Document type: Article