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Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth.
Pietras, Alexander; Katz, Amanda M; Ekström, Elin J; Wee, Boyoung; Halliday, John J; Pitter, Kenneth L; Werbeck, Jillian L; Amankulor, Nduka M; Huse, Jason T; Holland, Eric C.
Affiliation
  • Pietras A; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Alvord Brain Tumor Center, University of Washington, Seattle, WA 98104, USA; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA; Brain Tumor Center, Memorial Sloa
  • Katz AM; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA; Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  • Ekström EJ; Cell Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  • Wee B; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA; Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  • Halliday JJ; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA; Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  • Pitter KL; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA; Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  • Werbeck JL; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA; Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  • Amankulor NM; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Huse JT; Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA; Human Oncology and Pathogenesis Program and Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
  • Holland EC; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Alvord Brain Tumor Center, University of Washington, Seattle, WA 98104, USA. Electronic address: eholland@fhcrc.org.
Cell Stem Cell ; 14(3): 357-69, 2014 Mar 06.
Article in En | MEDLINE | ID: mdl-24607407

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Brain Neoplasms / Signal Transduction / Glioblastoma / Hyaluronan Receptors / Osteopontin / Stem Cell Niche Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2014 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Brain Neoplasms / Signal Transduction / Glioblastoma / Hyaluronan Receptors / Osteopontin / Stem Cell Niche Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2014 Document type: Article Country of publication: