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Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation.
Stavnezer, Janet; Linehan, Erin K; Thompson, Mikayla R; Habboub, Ghaith; Ucher, Anna J; Kadungure, Tatenda; Tsuchimoto, Daisuke; Nakabeppu, Yusaku; Schrader, Carol E.
Affiliation
  • Stavnezer J; Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and.
  • Linehan EK; Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and.
  • Thompson MR; Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and.
  • Habboub G; Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and.
  • Ucher AJ; Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and.
  • Kadungure T; Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and.
  • Tsuchimoto D; Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan.
  • Nakabeppu Y; Department of Immunobiology and Neuroscience, Medical Institute of Bioregulation, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan.
  • Schrader CE; Department of Microbiology and Physiological Systems, Immunology and Microbiology Program, University of Massachusetts Medical School, Worcester, MA 01655; and carol.schrader@umassmed.edu.
Proc Natl Acad Sci U S A ; 111(25): 9217-22, 2014 Jun 24.
Article in En | MEDLINE | ID: mdl-24927551
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Gene Expression Regulation, Enzymologic / Germinal Center / Somatic Hypermutation, Immunoglobulin / DNA-(Apurinic or Apyrimidinic Site) Lyase / DNA Repair / Endonucleases / Mutation Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Gene Expression Regulation, Enzymologic / Germinal Center / Somatic Hypermutation, Immunoglobulin / DNA-(Apurinic or Apyrimidinic Site) Lyase / DNA Repair / Endonucleases / Mutation Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2014 Document type: Article Country of publication: