Antioxidant properties of phenolic compounds from Baccharis articulata and B. usterii.
Nat Prod Commun
; 9(7): 941-2, 2014 Jul.
Article
in En
| MEDLINE
| ID: mdl-25230498
As a continuation of our research on the Baccharis genus, the evaluation of the antioxidant effect by TRAP and TBARS assays of three isolated compounds from n-butanol fractions of B. articulata and B. usterii is reported. The structures of these compounds were established as 4-O-beta-D-glucopyranosyl-3,5-dimethoxybenzyl-methanol (1), 5-O-[E]-dicaffeoylquinic acid (2), and 7-hydroxy-5,4'-dimethoxyflavone (3). In the TRAP assay it was possible to observe an antioxidant effect of both n-butanol fractions at 1.25 microg/mL. Among the isolated compounds, compound 2 displayed a remarkable contribution to the total antioxidant capacity of the n-butanol fraction of B. usterii. Moreover, the n-butanol fractions of both species, compounds 1 and 2 at 40.0 microg/mL were efficient in protection of lipid peroxidation in the TBARS experiment. They are promising lead compounds for use in medicinal chemistry studies.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phenols
/
Baccharis
/
Antioxidants
Language:
En
Journal:
Nat Prod Commun
Journal subject:
BOTANICA
/
FARMACOLOGIA
/
QUIMICA
Year:
2014
Document type:
Article
Country of publication: