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SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.
Li, Ling; Osdal, Tereza; Ho, Yinwei; Chun, Sookhee; McDonald, Tinisha; Agarwal, Puneet; Lin, Allen; Chu, Su; Qi, Jing; Li, Liang; Hsieh, Yao-Te; Dos Santos, Cedric; Yuan, Hongfeng; Ha, Trung-Quang; Popa, Mihaela; Hovland, Randi; Bruserud, Øystein; Gjertsen, Bjørn Tore; Kuo, Ya-Huei; Chen, Wenyong; Lain, Sonia; McCormack, Emmet; Bhatia, Ravi.
Affiliation
  • Li L; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Osdal T; Department of Clinical Science, Hematology Section, University of Bergen, Bergen 5021, Norway.
  • Ho Y; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Chun S; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • McDonald T; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Agarwal P; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Lin A; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Chu S; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Qi J; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Li L; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Hsieh YT; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Dos Santos C; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Yuan H; Department of Cancer Biology, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Ha TQ; Department of Clinical Science, Hematology Section, University of Bergen, Bergen 5021, Norway.
  • Popa M; KinN Therapeutics AS, Bergen 5008, Norway.
  • Hovland R; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen 5021, Norway.
  • Bruserud Ø; Department of Clinical Science, Hematology Section, University of Bergen, Bergen 5021, Norway; Department of Internal Medicine, Hematology Section, Haukeland University Hospital, Bergen 5021, Norway.
  • Gjertsen BT; Department of Clinical Science, Hematology Section, University of Bergen, Bergen 5021, Norway; Department of Internal Medicine, Hematology Section, Haukeland University Hospital, Bergen 5021, Norway.
  • Kuo YH; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Chen W; Department of Cancer Biology, City of Hope National Medical Center, Duarte, CA 91010, USA.
  • Lain S; Karolinska Institutet, Stockholm 17177, Sweden.
  • McCormack E; Department of Clinical Science, Hematology Section, University of Bergen, Bergen 5021, Norway; Department of Internal Medicine, Hematology Section, Haukeland University Hospital, Bergen 5021, Norway. Electronic address: emmet.mc.cormack@k2.uib.no.
  • Bhatia R; Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA. Electronic address: rbhatia@coh.org.
Cell Stem Cell ; 15(4): 431-446, 2014 Oct 02.
Article in En | MEDLINE | ID: mdl-25280219
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Leukemia, Myeloid, Acute / Proto-Oncogene Proteins c-myc / Drug Resistance, Neoplasm / Fms-Like Tyrosine Kinase 3 / Gene Regulatory Networks / Sirtuin 1 Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2014 Document type: Article Affiliation country:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Leukemia, Myeloid, Acute / Proto-Oncogene Proteins c-myc / Drug Resistance, Neoplasm / Fms-Like Tyrosine Kinase 3 / Gene Regulatory Networks / Sirtuin 1 Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2014 Document type: Article Affiliation country: