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Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands.
Nour, Afshin; Hayashi, Tomoko; Chan, Michael; Yao, Shiyin; Tawatao, Rommel I; Crain, Brian; Tsigelny, Igor F; Kouznetsova, Valentina L; Ahmadiiveli, Alast; Messer, Karen; Pu, Minya; Corr, Maripat; Carson, Dennis A; Cottam, Howard B.
Affiliation
  • Nour A; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Hayashi T; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Chan M; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Yao S; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Tawatao RI; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Crain B; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Tsigelny IF; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States; San Diego Supercomputer Center, and University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, United States; Department of Neurosciences, University of Cal
  • Kouznetsova VL; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States; San Diego Supercomputer Center, and University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, United States.
  • Ahmadiiveli A; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Messer K; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Pu M; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Corr M; Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0663, United States.
  • Carson DA; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
  • Cottam HB; Moores Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0819, United States.
Bioorg Med Chem Lett ; 24(21): 4931-8, 2014 Nov 01.
Article in En | MEDLINE | ID: mdl-25288184
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinazolines / Leukocytes, Mononuclear / Interleukin-8 / NF-kappa B / Interleukin-6 / Toll-Like Receptors / Toll-Like Receptor 4 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinazolines / Leukocytes, Mononuclear / Interleukin-8 / NF-kappa B / Interleukin-6 / Toll-Like Receptors / Toll-Like Receptor 4 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2014 Document type: Article Affiliation country: Country of publication: