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IFN-γ causes aplastic anemia by altering hematopoietic stem/progenitor cell composition and disrupting lineage differentiation.
Lin, Fan-ching; Karwan, Megan; Saleh, Bahara; Hodge, Deborah L; Chan, Tim; Boelte, Kimberly C; Keller, Jonathan R; Young, Howard A.
Affiliation
  • Lin FC; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD;
  • Karwan M; Laboratory of Animal Science, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD; and.
  • Saleh B; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD;
  • Hodge DL; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD;
  • Chan T; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD;
  • Boelte KC; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD;
  • Keller JR; Hematopoiesis and Stem Cell Biology Section, Center for Cancer Research, National Cancer Institute, Frederick, MD.
  • Young HA; Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Frederick, MD;
Blood ; 124(25): 3699-708, 2014 Dec 11.
Article in En | MEDLINE | ID: mdl-25342713

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Cell Differentiation / Interferon-gamma / Cell Lineage / Anemia, Aplastic Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2014 Document type: Article Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / Cell Differentiation / Interferon-gamma / Cell Lineage / Anemia, Aplastic Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2014 Document type: Article Country of publication: