Efficient synthesis of ethisterone glycoconjugate via bis-triazole linkage.
Carbohydr Res
; 399: 2-7, 2014 Nov 18.
Article
in En
| MEDLINE
| ID: mdl-25369262
ABSTRACT
Synthesis of sugar based triazolyl azido-alcohols was accomplished via one pot click reaction of glycosyl alkynes with epichlorohydrin in aqueous medium. All the developed triazolyl azido-alcohols were further utilized for the synthesis of bis-triazolyl ethisterone glycoconjugates using CuAAC reaction. The developed triazole-linked ethisterone glycoconjugates would be crucial in androgen receptor pharmacology and chemical biology.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Triazoles
/
Glycoconjugates
/
Ethisterone
Language:
En
Journal:
Carbohydr Res
Year:
2014
Document type:
Article
Affiliation country: