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Characterization of the binding properties of T-773 as a PET radioligand for phosphodiesterase 10A.
Harada, Akina; Suzuki, Kazunori; Miura, Shotaro; Hasui, Tomoaki; Kamiguchi, Naomi; Ishii, Tsuyoshi; Taniguchi, Takahiko; Kuroita, Takanobu; Takano, Akihiro; Stepanov, Vladimir; Halldin, Christer; Kimura, Haruhide.
Affiliation
  • Harada A; CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Suzuki K; CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Miura S; CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Hasui T; CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Kamiguchi N; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Ishii T; Biomolecular Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Taniguchi T; CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Kuroita T; CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan.
  • Takano A; Center for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Stepanov V; Center for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Halldin C; Center for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Kimura H; CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, Fujisawa, Japan. Electronic address: haruhide.kimura@takeda.com.
Nucl Med Biol ; 42(2): 146-54, 2015 Feb.
Article in En | MEDLINE | ID: mdl-25451212
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Pyrazoles / Pyridazines / Phosphoric Diester Hydrolases / Positron-Emission Tomography Limits: Animals / Humans / Male Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2015 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Pyrazoles / Pyridazines / Phosphoric Diester Hydrolases / Positron-Emission Tomography Limits: Animals / Humans / Male Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2015 Document type: Article Affiliation country: