In vitro interaction of mutagenic chromium (VI) with red blood cells.
FEBS Lett
; 257(1): 52-4, 1989 Oct 23.
Article
in En
| MEDLINE
| ID: mdl-2553494
ABSTRACT
The interaction of mutagenic Cr(VI) with red blood cells has been studied by ESR spectroscopy. Signals of two Cr(V) species are observed almost immediately after contacting red cells with chromate(VI) aqueous solution at pH 7.4. The signal at go = 1.985, which decays within one hour, is attributed to a Cr(V) complex formed by glutathione due its reducing and chelating ability. The other signal at go = 1.979, which is distinctly more persistent, may indicate that some immobilization of the formed Cr(V) ions takes place on the macromolecular cell components, e.g. glycoproteins.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chromates
/
Erythrocytes
/
Mutagens
Limits:
Adult
/
Humans
Language:
En
Journal:
FEBS Lett
Year:
1989
Document type:
Article
Affiliation country: