Long-lasting oral analgesic effects of N-protected aminophosphinic dual ENKephalinase inhibitors (DENKIs) in peripherally controlled pain.

Bonnard, Elisabeth; Poras, Hervé; Nadal, Xavier; Maldonado, Rafael; Fournié-Zaluski, Marie-Claude; Roques, Bernard P

Bonnard, Elisabeth; Poras, Hervé; Nadal, Xavier; Maldonado, Rafael; Fournié-Zaluski, Marie-Claude; Roques, Bernard P.

Affiliation

Bonnard E; Pharmaleads 75013, Paris, France.
Poras H; Pharmaleads 75013, Paris, France.
Nadal X; Laboratori de Neurofarmacologia, Universitat Pompeu Fabra, Parc de Recerca Biomedica de Barcelona (PRBB) Barcelona, Spain.
Maldonado R; Laboratori de Neurofarmacologia, Universitat Pompeu Fabra, Parc de Recerca Biomedica de Barcelona (PRBB) Barcelona, Spain.
Fournié-Zaluski MC; Pharmaleads 75013, Paris, France.
Roques BP; Pharmaleads 75013, Paris, France ; Université Paris-Descartes 75006, Paris, France.

Pharmacol Res Perspect ; 3(2): e00116, 2015 Mar.

Article in En | MEDLINE | ID: mdl-25692029

Key words

Enkephalinase inhibitors; enkephalin-gabapentin analgesic synergy; enkephalins; inflammation; neuropathic pain; peripherally controlled pain; pharmacological assay; physiological analgesia

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Pharmacol Res Perspect Year: 2015 Document type: Article Affiliation country:

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Pharmacol Res Perspect Year: 2015 Document type: Article Affiliation country: