In vitro metabolism and stability of the actinide chelating agent 3,4,3-LI(1,2-HOPO). | J Pharm Sci;104(5): 1832-8, 2015 May. | MEDLINE

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In vitro metabolism and stability of the actinide chelating agent 3,4,3-LI(1,2-HOPO).

Choi, Taylor A; Furimsky, Anna M; Swezey, Robert; Bunin, Deborah I; Byrge, Patricia; Iyer, Lalitha V; Chang, Polly Y; Abergel, Rebecca J.

Affiliation

Choi TA; Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California.

J Pharm Sci ; 104(5): 1832-8, 2015 May.

Article in En | MEDLINE | ID: mdl-25727482

Subject(s)
Key words

ADME; chelation therapy; cytochrome P450; intestinal absorption; microsomes; protein binding; stability

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Chelating Agents / Actinoid Series Elements / Heterocyclic Compounds, 1-Ring Limits: Animals / Female / Humans / Male Language: En Journal: J Pharm Sci Year: 2015 Document type: Article Country of publication:

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridones / Chelating Agents / Actinoid Series Elements / Heterocyclic Compounds, 1-Ring Limits: Animals / Female / Humans / Male Language: En Journal: J Pharm Sci Year: 2015 Document type: Article Country of publication: